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Archive for July, 2018

Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation

July 31st, 2018

Determination of reactive oxygen species (ROS) generation The intracellular amounts of reactive oxygen species (ROS) were measured in bone marrow cells and in whole cell, mitochondrial and cytosolic fraction of cardiac tissue homogenate by a fluorometric assay with DCFH-DA [28]. Briefly, bone marrow cells (2 × 106) and cardiac tissue homogenate (homogenized in Locke’s Buffer, […]